〜なしに（は）

Meaning

Means "without doing that" or "in a state where that is absent." In the form 「〜なしには〜ない」, it often takes a negative as a necessary condition.

Examples

十分な準備なしに、本番に臨むのは無謀だ。 It is reckless to face the real thing without adequate preparation.
彼女の苦労話は、涙なしには聞けなかった。 Her story of hardship cannot be listened to without tears.